Page 133 - Ageing and Dementia: A compendium of New Zealand research literature
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CONFERENCE PRESENTATIONS AND POSTERS ON AGEING AND DEMENTIAS 116
Campbell, D. (2014.). Alzheimer’s In M. Steur, & S. Gee (Eds.),
Sharing evidence, supporting Action:
Proceedings of the NDC Dementia Knowledge Exchange Forum 2013
(pp.87-90). Christchurch,
NZ: National Dementia Cooperative
Chacko, E. (2014). Driving assessment and beyond: An observational study. In M. Steur, & S. Gee (Eds.),
Sharing evidence, supporting Action: Proceedings of the NDC Dementia Knowledge Exchange
Forum 2013
(pp. 29-38). Christchurch, NZ: National Dementia Cooperative.
Chang, L. (2013, June). Alzheimer’s disease in the human eye – molecular evidence and prospective
clinical application. Paper presented at Brain Health Research Centre (BHRC) 7
th
Annual
Conference.
ABSTRACT
Alzheimer’s disease (AD) is the most common form of dementia with progressive deterioration of
memory and cognition. Complaints related to vision are common among AD patients, and over the years
researchers have investigated the cause of these visual complaints. Various groups have reported
molecular evidence of AD in the eyes of transgenic animals. In human, several changes in the retina,
lens and in the vasculature have been noted in the eyes of AD patients, which may be related to the
visual symptoms. The question still remains whether anatomical changes may be detected within the
eye before clinical diagnosis for AD is established. We are searching for candidate ocular biomarkers
that could enable diagnosis of AD through the detection of abnormal changes in ocular anatomy and
function.
